Grid has been my mainstay raid frame addon since, well since I first started healing on a little baby shaman. I like the clean nature of it, and that it's pretty customizable and easy view. I don't have a problem with little indicator lights to show me things like agro, curses, bubbles, etc., but I do have one thing I'd like to change.
I have not seen another Grid setup that looks like mine. Part of this may be that I have some bastardized German version leftover from the time I let Unbearabull take me on a UI ride (I really did like that UI though). So when you die now, it just says TOT, and something different for FD (I just notice that the box isn't grayed out). Ghost is still ghost though, so go figure.
My biggest challenge will be cleaning every scrap of Grid out of my UI folders. It was a mess when I realm transferred, and as I mentioned in my Carbonite post - my UI is in need of an overhaul. While it may be akin to rearranging the deck chairs on the Titanic (with Cataclysm sure to break and change everything), I figure that this is the best time to start playing with a new UI. The worst I have to fear is screwing up in a PUG raid (I do a GDKP to pay the bills for my alts), and given that most GDKPs don't go more than 8/12 - I can do those in my sleep.
I'm really not keen on Vuhdo, though I did give it a spin for a while when we first started working on LK. I like using mouse-over macros, not clique(esque) type setups, which Vuhdo seemed to use right out of the box. Sometimes I just want to target someone, and the last time I used click style macros I wiped the raid on the Four Horseman (Sorry Hanora).
Healbot got a bad name from way back when, and I've never really looked at it seriously. Part of my reasoning is I use Grid as my healing/raid frame package - I don't have separate frames out for anything else. I used to do this when I was raid leading in BC, but I've found that I can get all the info I need from Grid.
The rest of the UI
I'll be putting my whole UI up for others to look at, and I'm busy scouring the blogs for UIs to steal from. At this point anything is on the table, though I have gotten used to having things like a HUD, scrolling combat text, and my Razer. I definately need to move my map though. Trying to keep an eye on it while farming, leveling, and watching for Alliance is getting a bit much.